Anne Bassett

Titles and Positions:
Dalglish Chair in 22q Deletion Syndrome, University Health Network
Director, Clinical Genetics Research Program, Centre for Addiction and Mental Health

Area(s) of Special Interest:
Dalglish Family 22q Clinic


Dr. Anne Bassett is a world-renowned expert in adults with 22q11.2 deletions and in the genetics of complex conditions, predominantly major psychiatric and congenital cardiac disease. Her studies of tetralogy of Fallot have identified copy number variants and loss of function variants that have informed mechanism and changed clinical practice. Her research involves identifying rare genetic variants with high impact and delineating their lifelong expression, including neurodevelopmental/neuropsychiatric manifestations and medical conditions associated with these often multi-system genetic disorders. These studies showcase the enhanced power of molecularly identified genetic conditions, and in providing valuable animal models for studying complex diseases. Dr. Bassett plays a leading role in international consortia, including genome sequencing of ~1,500 individuals with 22q11.2 deletions, and in publishing pediatric and adult clinical practice guidelines for 22q11.2 deletion syndrome.

Dr. Bassett holds the Dalglish Chair in 22q11.2 Deletion Syndrome at the University Health Network (UHN) and University of Toronto, and is the Director of the Dalglish Family 22q Clinic at the Toronto General Hospital. A longstanding associate staff member of the Division of Cardiology at UHN, she is also an Associate Member of the Canadian College of Medical Geneticists. She is a Professor in the Department of Psychiatry at the University of Toronto and Director of the Clinical Genetics Research Program at the Centre for Addiction & Mental Health. As part of her public service, Dr. Bassett is the Medical Director for the International 22q Foundation, and a Founding Member of the 22q11.2 Society.